Probability of Neonatal Early-Onset Sepsis Based on Maternal Risk Factors and the Infant's Clinical Presentation
The tool below is intended for the use of clinicians trained and experienced in the care of newborn infants. Using this tool, the risk of early-onset sepsis can be calculated in an infant born > 34 weeks gestation. The interactive calculator produces the probability of early onset sepsis per 1000 babies by entering values for the specified maternal risk factors along with the infant's clinical presentation.
The tool below is intended for the use of clinicians trained and experienced in the care of newborn infants. Using this tool, the risk of early-onset sepsis can be calculated in an infant born > 34 weeks gestation. The interactive calculator produces the probability of early onset sepsis per 1000 babies by entering values for the specified maternal risk factors along with the infant's clinical presentation.
Caution
There may be ever-so-slight differences in the numbers when compared with the web calculator due to the official web calculator’s aggressive rounding at various stages.
There may be ever-so-slight differences in the numbers when compared with the web calculator due to the official web calculator’s aggressive rounding at various stages.
Please enter details below.
| Predictor | Input |
|---|---|
| Incidence of Early-Onset Sepsis ? | |
| Gestational age ? |
weeks
days
|
| Highest maternal antepartum temperature ? |
°C
Valid range: 35.0–41.5 °C (95.0–106.7 °F)
|
| ROM (Hours) ? | |
| Maternal GBS status ? |
|
| Type of intrapartum antibiotics ? |
|
| Risk per 1000/births | |
|---|---|
| EOS Risk @ Birth | — |
| EOS Risk after Clinical Exam | Risk per 1000/births | Clinical Recommendation ? | Vitals |
|---|---|---|---|
| Well Appearing ? | — | No culture, no antibiotics | Routine Vitals |
| Equivocal ? | — | Blood culture | Vitals every 4 hours for 24 hours |
| Clinical Illness ? | — | Empiric antibiotics | Vitals per NICU |
References
Puopolo KM, Draper D, Wi S, et al. Estimating the probability of neonatal early-onset infection on the basis of maternal risk factors. Pediatrics 2011;128(5):e1155–63. DOI: 10.1542/peds.2010-3464.
Acknowledgements
I wish a massive thank you to the team at Kaiser Permanente for developing the original 2017 Early-Onset Sepsis Calculator, for declaring it open-source, and for providing extensive related documentation and supplemental materials, including clear instructions on how to implement their calculations in local EMRs.
Contact
Contact me! Send your email to akshay.phakey@nhs.net